Dr. Guo
Dr. Qing Guo
Dr. Qing Guo received his M.D. degree in medicine in 1984, M.S degree in physiology in 1987, and Ph.D. in neurobiology in 1993. He pursued postdoctoral research in molecular biology of apoptosis under Professor Mark P. Mattson in Sanders-Brown Center on Aging at the University of Kentucky before he joined faculty in the Department of Neurobiology and Pharmacology at Northeastern Ohio Universities College of Medicine (NEOUCOM) in 1999. In 2003, Dr. Guo became an Associate Professor in the Department of Physiology at the University of Oklahoma Health Sciences Center.
Research in Dr. Guo's Group: Signaling of Cell Death in Physiology and Disease
CURRENT RESEARCH INTERESTS/AREAS: Many diseases in humans are associated with dysregulation of cell death and survival. Excessive cell death, via apoptosis, necrosis, or other forms of cell death, leads to lost of functional cells and is linked to diseases in various systems related to ischemia, myocardioinfarction, stroke, neurodegenerative disorders (including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and spinal muscular atrophy), renal failure, osteoporosis, and complications associated with diabetes and HIV infection.
Members of Dr. Guo's Group
Members of Dr. Guo's lab can be found at: http://ouhscphysio.org/?q=image/tid/17
Selected Publications from Dr. Guo's Group
1. Daniel J. Payette, Jun Xie, Najeeb Shirwany, and Qing Guo. Exacerbation of apoptosis of cortical neurons following traumatic brain injury in Par-4 transgenic mice. International Journal of Clinical and Experimental Pathology 2008; 1: 44-56
2. Najeeb A Shirwany, Daniel Payette, and Qing Guo. The amyloid beta ion channel hypothesis of Alzheimer’s disease: A review. Neuropsychiatric Disease and Treatment. 2007: 3(5) 597-612.
FUNDING SOURCES
Research in Dr. Guo’s group has been funded by the following local, state and federal agencies:
• Regulation of APP Processing by Par-4
Principal Investigator: Qing Guo, Ph.D.
Agency: NIH/NINDS
Type: R01
• AATF and Renal Protection
Principal Investigator: Qing Guo, Ph.D.
Agency: NIH/NIDDK
Type: R01
• Regulation of ChAT Activity in Cholinergic Neurons by Par-4.
Principal Investigator: Qing Guo, Ph.D.
Agency: Alzheimer’s Association
Type: New Investigator Initiated Research Grant
Employment Opportunities Available in Dr. Guo's Lab
We are currently seeking motivated scientists who specialize in braod areas of cellular and molecular biology. Experience in transgenic animals, cell death analysis, and gene transfer/targeting is desirable. If you are interested in joining our team as a research faculty, postdoctoral fellow/associate or assistant, please feel free to contact Dr. Qing Guo at 405-271-2226 ext. 56268, or e-mail him at qing-guo@ouhsc.edu. Positions are contingent upon availability of funds.
